How to create multi-color border with CSS?

body {
  background: #ccc;
}

.box {
  text-align: center;
  position: relative;
  line-height: 100px;
  background: #fff;
  height: 100px;
  width: 300px;
}

.box:after {
  background: linear-gradient(to right, #bcbcbc 25%,#ffcd02 25%, #ffcd02 50%, #e84f47 50%, #e84f47 75%, #65c1ac 75%);
  position: absolute;
  content: '';
  height: 4px;
  right: 0;
  left: 0;
  top: 0;
}

<div class="box">Div</div>