对于对话框中的键盘加速器，我这样做：

在OnInitDialog中

BOOL CMyDlg::OnInitDialog()
{
   ...
   m_hAccel = LoadAccelerators ( AfxGetResourceHandle(), MAKEINTRESOURCE(IDR_DLGACCEL));
   ...
}

PreTranslateMessage

BOOL CMyDlg::PreTranslateMessage(MSG* pMsg)
{
  if (m_hAccel)
  {
    if (::TranslateAccelerator(m_hWnd, m_hAccel, pMsg))
      return(TRUE);
    else
      return CDialog::PreTranslateMessage(pMsg);
  }
  else
    return CDialog::PreTranslateMessage(pMsg);
}

在OnDestroy

void CMyDlg::OnDestroy()
{
  ...
  VERIFY(DestroyAcceleratorTable(m_hAccel)) ;
  CDialog::OnDestroy();
}

消息图：

BEGIN_MESSAGE_MAP(CMyDlg, CDialog)
  ...
  ON_COMMAND(IDC_SOMECOMMANDID, OnDoSomething)
  ON_UPDATE_COMMAND_UI(IDC_SOMECOMMANDID, OnUpdateDoSomething)
  ...
END_MESSAGE_MAP()

命令处理程序

void CMyDlg::OnUpdateDoSomething(CCmdUI* pCmdUI) 
{
  ...
  pCmdUI->Enable(...) ;
}

void CMyDlg::OnDoSomething() 
{
  ...
}

.rc文件中的加速器表

IDR_DLGACCEL ACCELERATORS
BEGIN
    "A",            IDC_SOMECOMMANDID,         VIRTKEY, CONTROL, NOINVERT  // Ctrl+A
    ...
END

就这样。